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ANTIVIRAL EFFECTS OF BACTERIOCIN AGAINST ANIMAL-TO-HUMAN TRANSMITTABLE MUTATED SARS-COV-2: A SYSTEMATIC

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 4,   Pages 603-622 doi: 10.15302/J-FASE -2021397

Abstract:

The COVID-19 infections caused by SARS-CoV-2 have resulted in millions of people being infected andDespite possessing antiviral traits the potential of bacteriocins to combat SARS-CoV-2 infection hasThese antimicrobial peptides have been suggested as effective antiviral therapeutics and therapeuticThis review also provides a new insight into the cellular and molecular alterations which have made SARS-CoVuse with synthetic biology and nanosensor technology for rapid detection.

Keywords： antimicrobial proteins / antiviral profiling of bacteriocins / antiviral therapeutics / immunomodulation/ nanosensor technology / mutated SARS-CoV-2    

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Human monoclonal antibodies as candidate therapeutics against emerging viruses

Yujia Jin, Cheng Lei, Dan Hu, Dimiter S. Dimitrov, Tianlei Ying

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 462-470 doi: 10.1007/s11684-017-0596-6

Abstract:

The emergence of new pathogens, such as severe acute respiratory syndrome coronavirus (SARS-CoV),Middle East respiratory syndrome coronavirus (MERS-CoV), and Ebola virus, poses serious challenges toglobal public health and highlights the urgent need for novel antiviral approaches.We also review the application of recently developed human mAbs against SARS-CoV, MERS-CoV, and Ebola

Keywords： human monoclonal antibodies     emerging infectious diseases     SARS-CoV     MERS-CoV     Ebola virus    

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SARS-CoV-2 vaccine research and immunization strategies for improved control of the COVID-19 pandemic

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 185-195 doi: 10.1007/s11684-021-0913-y

Abstract: record speed at which Chinese scientists identified severe acute respiratory syndrome coronavirus 2 (SARS-CoVFurther research should be undertaken to develop more effective vaccines against SARS-CoV-2 variants

Keywords： COVID-19     pandemics     SARS-CoV-2     vaccination    

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Neutralization against SARS-CoV-2 Delta/Omicron variants and B cell response after inactivated vaccination

Frontiers of Medicine 2023, Volume 17, Issue 4,   Pages 747-757 doi: 10.1007/s11684-022-0954-x

Abstract: Emerging SARS-CoV-2 variants have made COVID-19 convalescents susceptible to re-infection and have raisedthe participants were followed up at 3.3 (Visit 1), 9.2 (Visit 2), and 18.5 (Visit 3) months after SARS-CoVSimilarly, the responses of SARS-CoV-2 RBD-specific B cells and memory B cells were boosted by the secondadministration of the inactivated vaccine (one or two doses), which enhanced neutralization against highly mutatedSARS-CoV-2 variants and memory B cell responses.

Keywords： COVID-19 convalescent     SARS-CoV-2     inactivated vaccination     neutralizing antibody     B cell response    

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Persistence of humoral and cellular immune response after SARS-CoV-2 infection: opportunities and challenges

Tangchun Wu

Frontiers of Medicine 2020, Volume 14, Issue 6,   Pages 816-819 doi: 10.1007/s11684-020-0823-4

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SARS-CoV-2 variants, immune escape, and countermeasures

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 196-207 doi: 10.1007/s11684-021-0906-x

Abstract: SARS-CoV-2 variants have aroused great concern and are expected to continue spreading.

Keywords： SARS-CoV-2     COVID-19     vaccine     immune escape     breakthrough     prevention    

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Neutralizing monoclonal antibodies present new prospects to treat SARS-CoV-2 infections

Rongtao Lai, Tianhui Zhou, Xiaogang Xiang, Jie Lu, Haiguang Xin, Qing Xie

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 644-648 doi: 10.1007/s11684-021-0847-4

Abstract: development of a broadly neutralizing antibody against severe acute respiratory syndrome coronavirus 2 (SARS-CoVreceptor-binding domain (RBD) of the spike (S) protein is the main target of neutralizing antibodies when SARS-CoV

Keywords： neutralizing antibody     antibody cocktail     SARS-CoV-2     COVID-19     therapeutic strategy    

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Less attention paid to waterborne SARS-CoV-2 spreading in Beijing urban communities

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 5, doi: 10.1007/s11783-021-1398-2

Abstract:

• A survey on individual’s perception of SARS-CoV-2 transmission was

Keywords： Environmental dissemination     Risk communication     Individual perception    

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Durability of neutralizing antibodies and T-cell response post SARS-CoV-2 infection

Yun Tan, Feng Liu, Xiaoguang Xu, Yun Ling, Weijin Huang, Mingquan Guo, Ziyu Fu, Dongguo Liang, Miao Xu, Hongzhou Lu, Saijuan Chen

Frontiers of Medicine 2020, Volume 14, Issue 6,   Pages 746-751 doi: 10.1007/s11684-020-0822-5

Abstract: is caused by a newly discovered β coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoVHow long the adaptive immunity triggered by SARS-CoV-2 can last is of critical clinical relevance inAll samples were positive for IgGs against the S- and N-proteins of SARS-CoV-2.a pseudovirus assay, with no difference in blocking the cell-entry of the 614D and 614G variants of SARS-CoVTogether, these results indicate that durable anti-SARS-CoV-2 immunity is common in convalescent population

Keywords： SARS-CoV-2     neutralizing antibodies     T-cell response    

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Occurrence and Decay of SARS-CoV-2 in Community Sewage Drainage Systems Article

Qian Dong, Jun-Xiong Cai, Yan-Chen Liu, Hai-Bo Ling, Qi Wang, Luo-Jing Xiang, Shao-Lin Yang, Zheng-Sheng Lu,Yi Liu,Xia Huang, Jiu-Hui Qu

Engineering 2023, Volume 26, Issue 7,   Pages 214-219 doi: 10.1016/j.eng.2022.03.012

Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes COVID-19, can be dischargedHowever, a comprehensive understanding of the occurrence, presence, and potential transmission of SARS-CoVThe results indicated that the risk of long-term emission of SARS-CoV-2 to the environment via vent stacksSARS-CoV-2 were mainly detected in the liquid phase, as opposed to being detected in aerosols, and itsThe surveillance of SARS-CoV-2 in sewage could be a sensitive indicator for the possible presence of

Keywords： SARS-CoV-2     Transmission risk     Drainage system     Sewage     Community    

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Neurological manifestations of patients with COVID-19: potential routes of SARS-CoV-2 neuroinvasion from

Zhengqian Li, Taotao Liu, Ning Yang, Dengyang Han, Xinning Mi, Yue Li, Kaixi Liu, Alain Vuylsteke, Hongbing Xiang, Xiangyang Guo

Frontiers of Medicine 2020, Volume 14, Issue 5,   Pages 533-541 doi: 10.1007/s11684-020-0786-5

Abstract: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoVrespiratory distress, characteristic neurological manifestations are also described, indicating that SARS-CoV, laryngopharynx, trachea, lower respiratory tract, alveoli epithelium, or gastrointestinal mucosa, SARS-CoV

Keywords： coronavirus disease 2019 (COVID-19)     SARS-CoV-2     neurological manifestations     neuroinvasion     brain    

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Protection of inactivated vaccine against SARS-CoV-2 infections in patients with comorbidities: a prospective

Frontiers of Medicine   Pages 867-877 doi: 10.1007/s11684-023-0995-9

Abstract: Protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection of inactivatedWe compared the risk of SARS-CoV-2 infection after complete vaccination with Sinopharm/BBIBP in peopleprimary series of vaccination with Sinopharm/BBIBP in Bangkok, Thailand were prospectively followed for SARS-CoVThe protection against SARS-CoV-2 infection of the Sinopharm vaccine was similar in participants with

Keywords： COVID-19     Sinopharm/BBIBP vaccine     immunocompromised patients     real-world    

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SARS-CoV-2 Entry Factors: ACE2 and TMPRSS2 Are Expressed in Peri-Implantation Embryos and Article

Wei Chen, Peng Yuan, Ming Yang, Zhiqiang Yan, Siming Kong, Jie Yan, Xixi Liu, Yidong Chen, Jie Qiao, Liying Yan

Engineering 2020, Volume 6, Issue 10,   Pages 1162-1169 doi: 10.1016/j.eng.2020.07.013

Abstract:

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread throughout the world, leadingAngiotensin-converting enzyme 2 (ACE2) is the receptor of both severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2.In order to investigate the potential risk of SARS-CoV-2 vertical transmission, we explored ACE2These findings indicate that there may be different SARS-CoV-2 infection susceptibilities of D6 embryos

Keywords： SARS-CoV-2     ACE2     Vertical transmission     Placenta     Peri-implantation    

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operation of extra-large Fangcang hospitals: experience and lessons from containing the highly contagious SARS-CoV

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 165-171 doi: 10.1007/s11684-022-0961-y

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Influenza's Plummeting during the COVID-19 Pandemic: The Roles of Mask-Wearing, Mobility Change, and SARS-CoV Article

Shasha Han, Ting Zhang, Yan Lyu, Shengjie Lai, Peixi Dai, Jiandong Zheng, Weizhong Yang, Xiao-Hua Zhou, Luzhao Feng

Engineering 2023, Volume 21, Issue 2,   Pages 195-202 doi: 10.1016/j.eng.2021.12.011

Abstract: mobility changes (international and domestic), and severe acute respiratory syndrome coronavirus 2 (SARS-CoVOnly in 2019–2020, SARS-CoV-2 interference had statistically significant effects.

Keywords： Influenza     Mask-wearing     Mobility mitigation     SARS-CoV-2 interference     Non-pharmaceutical interventions    

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Title Author Date Type Operation

ANTIVIRAL EFFECTS OF BACTERIOCIN AGAINST ANIMAL-TO-HUMAN TRANSMITTABLE MUTATED SARS-COV-2: A SYSTEMATIC

Journal Article

Human monoclonal antibodies as candidate therapeutics against emerging viruses

Yujia Jin, Cheng Lei, Dan Hu, Dimiter S. Dimitrov, Tianlei Ying

Journal Article

SARS-CoV-2 vaccine research and immunization strategies for improved control of the COVID-19 pandemic

Journal Article

Neutralization against SARS-CoV-2 Delta/Omicron variants and B cell response after inactivated vaccination

Journal Article

Persistence of humoral and cellular immune response after SARS-CoV-2 infection: opportunities and challenges

Tangchun Wu

Journal Article

SARS-CoV-2 variants, immune escape, and countermeasures

Journal Article

Neutralizing monoclonal antibodies present new prospects to treat SARS-CoV-2 infections

Rongtao Lai, Tianhui Zhou, Xiaogang Xiang, Jie Lu, Haiguang Xin, Qing Xie

Journal Article

Less attention paid to waterborne SARS-CoV-2 spreading in Beijing urban communities

Journal Article

Durability of neutralizing antibodies and T-cell response post SARS-CoV-2 infection

Yun Tan, Feng Liu, Xiaoguang Xu, Yun Ling, Weijin Huang, Mingquan Guo, Ziyu Fu, Dongguo Liang, Miao Xu, Hongzhou Lu, Saijuan Chen

Journal Article

Occurrence and Decay of SARS-CoV-2 in Community Sewage Drainage Systems

Qian Dong, Jun-Xiong Cai, Yan-Chen Liu, Hai-Bo Ling, Qi Wang, Luo-Jing Xiang, Shao-Lin Yang, Zheng-Sheng Lu,Yi Liu,Xia Huang, Jiu-Hui Qu

Journal Article

Neurological manifestations of patients with COVID-19: potential routes of SARS-CoV-2 neuroinvasion from

Zhengqian Li, Taotao Liu, Ning Yang, Dengyang Han, Xinning Mi, Yue Li, Kaixi Liu, Alain Vuylsteke, Hongbing Xiang, Xiangyang Guo

Journal Article

Protection of inactivated vaccine against SARS-CoV-2 infections in patients with comorbidities: a prospective

Journal Article

SARS-CoV-2 Entry Factors: ACE2 and TMPRSS2 Are Expressed in Peri-Implantation Embryos and

Wei Chen, Peng Yuan, Ming Yang, Zhiqiang Yan, Siming Kong, Jie Yan, Xixi Liu, Yidong Chen, Jie Qiao, Liying Yan

Journal Article

operation of extra-large Fangcang hospitals: experience and lessons from containing the highly contagious SARS-CoV

Journal Article

Influenza's Plummeting during the COVID-19 Pandemic: The Roles of Mask-Wearing, Mobility Change, and SARS-CoV

Shasha Han, Ting Zhang, Yan Lyu, Shengjie Lai, Peixi Dai, Jiandong Zheng, Weizhong Yang, Xiao-Hua Zhou, Luzhao Feng

Journal Article